Author

Shiroma Mangalika Handunnetti

Institute of Biochemistry, Molecular Biology and BiotechnologyORCID 0000-0002-0051-7232Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Darshan De Silva· 1 shared Gayani PremawansaiD· 1 shared Hansani Gunasekara· 1 shared Maheshi MapalagamageiD· 1 shared Nipuni Chandrasiri· 1 shared Sunil PremawansaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Darshan De Silva

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1 paper

Recent·Most cited

In vitro effects of selected angiogenesis-promoting drugs on human Ea.hy926 endothelial cells treated with critical-stage dengue hemorrhagic fever serum

Nipuni Chandrasiri, Maheshi Mapalagamage, Hansani Gunasekara, Darshan De Silva, Gayani Premawansa, Shiroma Mangalika Handunnetti, Sunil Premawansa

This study evaluates the effects of Simvastatin, Phenytoin, and Ascorbic acid on endothelial dysfunction in Ea.hy926 cells treated with DHF serum, finding that low-dose Simvastatin reduces cell-cell distances and increases cell size.

bioRxiv · Sep 19, 2025 · PreprintImmunology