An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells
David A Turner, Jamie Trott, Penelope Hayward, Pau Rué, Alfonso Martinez Arias
This study investigates how extracellular signaling and pluripotency loss dynamics influence cell fate decisions in mouse ES cells, finding that Wnt signaling supports both neuroectoderm and primitive streak fates.
Biology Open · Jun 20, 2014Peer-reviewedDevelopmental Biology