The fine-tuning of synapse development by oxidative stress and autophagy requires presynaptic ATM kinase
Matthew J. Taylor, Syed Azan Ahmed, Ellena G. Badenoch, David Bennett, Richard I. Tuxworth
This study shows that presynaptic ATM kinase in Drosophila coordinates autophagy and oxidative stress responses to regulate synapse development and prevent neurodegeneration.
bioRxiv · Apr 25, 2024 · PreprintDevelopmental Biology