Sex-specific long-term alteration of hippocampal excitation/inhibition balance and behavior by transient caffeine exposure during synaptogenesis
Solen Rimbert, Jessica C. Pressey, Ferran Gomez Castro, Zahra Imani, Marion Russeau, David Blum, Marika Nosten‐Bertrand, Sabine Lévi
This study shows that caffeine exposure during synaptogenesis causes sex-specific changes in hippocampal synaptic development and behavior, with distinct effects on anxiety, memory, and seizure susceptibility.
bioRxiv · Sep 3, 2026 · PreprintNeuroscience