Mapping the reactive cysteine landscape of the NOD-like receptor pyrin domain-containing 3 protein
Bjoern K Ziehr, Bruno C Amaral, David C Schriemer, Justin A MacDonald
This study identifies reactive cysteine residues in NLRP3 and shows how their oxidation by ROS affects NLRP3 conformation and inflammasome activation.
bioRxiv · Nov 9, 2026 · PreprintBiochemistry