Contributions of single-cell mechanics and cell-cell adhesion to multicellular spheroid mechanics
David Dolgitzer, Eleana Parajón, Douglas N. Robinson, Pablo A. Iglesias
This study uses a computational model to show that cell-cell adhesion has a greater impact on spheroid elasticity than single-cell stiffness, while both influence viscoelastic relaxation.
bioRxiv · Aug 9, 2026 · PreprintBiophysics