Eleana Parajón

This study uses a computational model to show that cell-cell adhesion has a greater impact on spheroid elasticity than single-cell stiffness, while both influence viscoelastic relaxation.

The paper screens compounds to identify mechanical mediators by measuring cell deformability, finding NUDT5 as a key mediator in ovarian cancer.

This study shows that Ras activity has a biphasic effect on cell migration, with both high and low activity impairing movement, and reveals that Ras regulates migration through rapid, non-transcriptional mechanisms.