A single closed head injury in mice induces chronic, progressive white matter atrophy and increased phospho-tau expressing oligodendrocytes
David F. Havlicek, Rachel Furhang, Elena Nikulina, Bayle Smith-Salzberg, Siobhán Lawless, Sasha A. Sevarin, Sevara Mallaboeva, Fizza Nayab, Alan C. Seifert, John F. Crary, Peter John Bergold
This study shows that a single closed head injury in mice causes chronic white matter atrophy and increased phospho-tau in oligodendrocytes, differing from chronic traumatic encephalopathy from repeated injuries.
bioRxiv · May 19, 2022 · PreprintNeuroscience