Author

David Golan

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Genomics· 1

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Research Focus:GWAS / association mapping· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

David A. KnowlesiD· 2 shared Alvaro BarbeiraiD· 1 shared Anand BhaskariD· 1 shared Anshul Bharat KundajeiD· 1 shared Arno RuusaleppiD· 1 shared Audrey Qiuyan FuiD· 1 shared Bogdan PaşaniuciD· 1 shared Diego CalderoniD· 1 shared

Activity by Year

2016-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersGenetics

David A. KnowlesORCID

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3 papers

Recent·Most cited

Transcriptome-wide association studies: opportunities and challenges

Michael Wainberg, Nasa Sinnott-Armstrong, Nicholas Mancuso, Alvaro Barbeira, David A. Knowles, David Golan, Raili Ermel, Arno Ruusalepp, Thomas Quertermous, Ke Hao, Johan Björkegren, Hae Kyung Im, Bogdan Paşaniuc, Manuel A. Rivas, Anshul Bharat Kundaje

This paper evaluates transcriptome-wide association studies (TWAS) for causal gene prioritization, showing its strengths and limitations in identifying causal genes at GWAS loci.

Nature Genetics · Mar 29, 2019Peer-reviewedGenetics

Inferring Relevant Cell Types For Complex Traits Using Single-Cell Gene Expression

Diego Calderon, Anand Bhaskar, David A. Knowles, David Golan, Towfique Raj, Audrey Qiuyan Fu, Jonathan K. Pritchard

RolyPoly links GWAS summary statistics with single-cell RNA-seq to identify trait-relevant cell types and genes, finding associations between microglia and Alzheimer's disease, and oligodendrocytes and schizophrenia.

The American Journal of Human Genetics · Oct 26, 2017Peer-reviewedGenomics

Detection of human adaptation during the past 2,000 years

Yair Field, Evan A Boyle, Natalie Telis, Ziyue Gao, Kyle J Gaulton, David Golan, Loic Yengo, Ghislain Rocheleau, Philippe Froguel, Mark I McCarthy, Jonathan K Pritchard

This study detects recent human adaptation over the past 2,000 years using the Singleton Density Score, revealing selection signals for lactase, HLA, height, and other complex traits.

bioRxiv · May 7, 2016Genetics