Author

David N.W. Doell

University of Alberta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angie Chen· 1 shared Courtney MowatiD· 1 shared Felix Meier‐Stephenson· 1 shared Kristi BakeriD· 1 shared Shayla R. MosleyiD· 1 shared Siwon Choi· 1 shared Vanessa Meier‐StephensoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Angie Chen

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1 paper

Recent·Most cited

Mechanisms of genomic instability dictate cytosolic DNA composition and dendritic cell mediated anti-tumor immunity

Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier‐Stephenson, Vanessa Meier‐Stephenson, Kristi Baker

The paper shows that genomic instability in MSI CRCs generates cytosolic DNA that enhances STING activation and anti-tumor immunity via dendritic cells, suggesting improved DNA-based therapies for CIN CRCs.

Cell Reports · Jan 24, 2025Peer-reviewedCancer Biology