Viral delivery of compact CRISPR-Cas12f for in vivo gene editing applications
Allison M. Sharrar, Zuriah A. Meacham, Johanna Staples-Ager, Luisa Arake de Tacca, David Rabuka, Trevor N. Collingwood, Michael W. Schelle
This paper demonstrates efficient in vivo CRISPR gene editing using a compact Cas12f system delivered via AAV, showing safety and targeting multiple cell types.
bioRxiv · Feb 6, 2024 · PreprintMolecular Biology