An EcR probe reveals mechanisms of the ecdysone-mediated switch from repression-to-activation on target genes in the larval wing disc
Joanna Wardwell‐Ozgo, Douglas Terry, Colby K. Schweibenz, Michael Tu, Ola Solimon, David Schofeld, Kenneth H. Moberg
The paper uses an EcR-binding fragment to study how ecdysone (20E) switches EcR from repression to activation in larval wing discs, revealing spatial and target-specific regulation.
bioRxiv · Apr 7, 2022 · PreprintDevelopmental Biology