Kenneth H. Moberg

This study shows that the Yki:Tai interaction in Drosophila germline niche escort cells regulates BMP signaling and maintains stem cell fate by controlling Dpp ligand spread.

This study identifies a female-specific role for Nab2 in regulating insulin signaling and fat storage through neuronal control of dilp2 and dilp5 mRNA levels in Drosophila.

This study shows that mild head trauma in Drosophila leads to age-dependent neurodegeneration, with females being more affected due to reproductive signaling.

The paper shows that local ecdysone synthesis in Drosophila wing blastemas sustains developmental delay and promotes regeneration by maintaining EcR activity.

This paper identifies Nab2-regulated splicing of trio mRNA as critical for balancing Trio GEF domains and shaping axon and dendrite morphology in Drosophila neurons.

The paper shows that Taiman promotes epithelial cell fitness by controlling the Wg gradient through Dally-like glypican, leading to cell competition in Drosophila wing discs.

This study identifies Nab2's role in regulating m6A-dependent splicing of Sxl in Drosophila neuronal tissue, linking it to developmental and behavioral phenotypes.

This study identifies the Hippo pathway's role in Drosophila eye development through the interaction of Yorkie and Bonus, showing they control cell fate by promoting epidermal and antennal fates over eye fate.

The paper uses an EcR-binding fragment to study how ecdysone (20E) switches EcR from repression to activation in larval wing discs, revealing spatial and target-specific regulation.

This study identifies RNA interactomes of Drosophila Nab2 and Ataxin-2, showing they share RNA targets and regulate neuronal morphology.

This study shows Nab2 regulates dendritic arbors and axon projection through the planar cell polarity pathway in Drosophila.

This study shows that repetitive mild head trauma in Drosophila causes long-term brain deficits, worsened in females, and links increased neuronal activity to chronic degeneration.

This study shows ZC3H14 localizes to synapses, affects dendritic spine morphology, and dysregulates synaptic CaMKII levels upon loss of function.

The paper identifies genetic interactions between Nab2 and the planar cell polarity pathway in Drosophila, linking Nab2 to PCP-regulated processes like axon guidance and F-actin dynamics.

This study uses a Drosophila model to show that mutations in EXOSC3 cause neuronal dysfunction by altering RNA exosome function and affecting key neuronal RNAs.

The paper shows that an enhancer with specific binding sites can induce Notch haploinsufficiency phenotypes in Drosophila with wild-type Notch gene dose by promoting rapid Notch turnover through a bind and discard mechanism.