Parallel multiOMIC analysis reveals glutamine deprivation enhances directed differentiation of renal organoids
Iman Sarami, Katherine Elizabeth Hekman, Ashwani Gupta, Justin M. Snider, David Z Ivancic, Manja M. Zec, Manoj Kandpal, Issam Ben‐Sahra, Rajasree Menon, Edgar A. Otto, Floyd H. Chilton, Jason A. Wertheim
This study shows that glutamine deprivation promotes podocyte maturation in renal organoids through metabolic and transcriptomic changes during differentiation.
bioRxiv · Feb 27, 2025 · PreprintBioengineering