The landscape of toxic intermediates in the metabolic networks of pathogenic fungi reveals targets for antifungal drugs
Jan Ewald, Paul Mathias Jansen, Sascha Brunke, Davina Hiller, Christian H. Luther, Humberto González‐Díaz, Marcus T. Dittrich, André Fleißner, Bernhard Hube, Stefan Schuster, Christoph Kaleta
The paper identifies toxic intermediates in fungal metabolic pathways as potential antifungal targets using a random forest model and provides a web-service for exploration.
bioRxiv · Sep 5, 2021 · PreprintSystems Biology