Author

Marcus T. Dittrich

University of WürzburgORCID 0000-0002-7726-5491Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Amanda M. LaueriD· 1 shared André FleißneriD· 1 shared Andreas FriebeiD· 1 shared Barbara VonaiD· 1 shared Bernhard HubeiD· 1 shared Christian H. LutheriD· 1 shared Christoph KaletaiD· 1 shared Cordula Neuner· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Amanda M. LauerORCID

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Author profile →

3 papers

Recent·Most cited

FRMPD4, a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss

Daniel Liedtke, K Rak, Katrina M. Schrode, Philip Hehlert, Niloofar Chamanrou, Daniel Bengl, Radoslaw Katana, Soganad Heydaran, Julia Doll, Mei Han, Indrajit Nanda, Pingkalai R. Senthilan, Lukas Juergens, Linda Bieniussa, Johannes Voelker, , Barbara Vona

The paper identifies FRMPD4 as a causal gene for X-linked non-syndromic hearing loss through genetic analysis and cross-species functional studies.

medRxiv · Mar 30, 2026 · PreprintGenetic & Genomic Medicine

The landscape of toxic intermediates in the metabolic networks of pathogenic fungi reveals targets for antifungal drugs

Jan Ewald, Paul Mathias Jansen, Sascha Brunke, Davina Hiller, Christian H. Luther, Humberto González‐Díaz, Marcus T. Dittrich, André Fleißner, Bernhard Hube, Stefan Schuster, Christoph Kaleta

The paper identifies toxic intermediates in fungal metabolic pathways as potential antifungal targets using a random forest model and provides a web-service for exploration.

bioRxiv · Sep 5, 2021 · PreprintSystems Biology

cGMP signaling: probing antagonistic cyclic nucleotide platelet signals by modeling and experiment

Tim Breitenbach, Nils Englert, Özge Osmanoğlu, Natalia Rukoyatkina, Gaby Wangorsch, Andreas Friebe, Elke Butt, Robert Feil, Marcus T. Dittrich, Stepan P. Gambaryan, Thomas Dandekar

The paper develops and validates a model of cGMP signaling and VASP phosphorylation in platelets using data-driven approaches and experimental validation.

bioRxiv · Feb 1, 2021 · PreprintSystems Biology