A rhesus macaque model of Asia lineage Zika virus infection
Dawn M. Dudley, Matthew T. Aliota, Emma Mohr, Andrea M. Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, Meghan E. Breitbach, Mustafa N. Rasheed, Christina M. Newman, Dane D. Gellerup, Louise H. Moncla, Jennifer Post, Nancy Schultz-Darken, Michele L. Schotkzo, , David H. O’Connor
This study infects rhesus macaques with Asian lineage Zika virus to model infection in pregnant and non-pregnant individuals, showing prolonged viremia in pregnant animals and protective immunity after rechallenge.
bioRxiv · May 10, 2016 · PreprintPathology