Primary-Level Meta-Analysis of Diversity Outbred Mice Identifies a Fasting Plasma Trimethylamine N-Oxide (TMAO) Locus Modified by Sex and Diet
Kristen J. Sutton, Levi W. Evans, Erik Gertz, Dawson Budke, M. Nazmul Huda, Phoebe Yam, Myungsuk Kim, Jennifer M. Rutkowsky, Diana M. Shih, Jaana Hartiala, Daniel Pomp, Aldons Jake Lusis, Hooman Allayee, Brian J. Bennett
The paper identifies a TMAO locus on mouse chromosome 12 modified by sex and diet through a meta-analysis of 1,482 Diversity Outbred mice.
bioRxiv · Jun 24, 2026 · PreprintGenetics