Author

Brian J. Bennett

Agricultural Research ServiceORCID 0000-0002-0766-3195Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Physiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:mouse· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Assay:metabolomics· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Aldons Jake LusisiD· 2 shared Diana M. ShihiD· 2 shared Hooman AllayeeiD· 2 shared M. Nazmul HudaiD· 2 shared Adam DavidovichiD· 1 shared Adrian IdriziiD· 1 shared Andrew P. FeinbergiD· 1 shared Anna C. SalvadoriD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenetics

Aldons Jake LusisORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 11, 2026

Serine metabolism changes link sphingolipid and one-carbon metabolism to cardiovascular risk factors in a cross-sectional study of asymptomatic adults

Mengjiang Huang, Debra K. Tacad, Tong Shen…·John W. I. Newman

DOI 10.64898/2026.09.20.753050

humanmetabolomics

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GeneticsbioRxivPreprintJun 24, 2026

Primary-Level Meta-Analysis of Diversity Outbred Mice Identifies a Fasting Plasma Trimethylamine N-Oxide (TMAO) Locus Modified by Sex and Diet

Kristen J. Sutton, Levi W. Evans, Erik Gertz…·Brian J. Bennett

The paper identifies a TMAO locus on mouse chromosome 12 modified by sex and diet through a meta-analysis of 1,482 Diversity Outbred mice.

DOI 10.64898/2026.06.19.733321

mousemetabolomics

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PhysiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedAug 14, 2025

Trimethylamine-N-oxide affects cell type-specific pathways and networks in mouse aorta to promote atherosclerotic plaque vulnerability

Jenny Yeuk‐Ki Cheng, Michael Cheng, Satyesh K. Sinha…·Diana M. Shih

This study shows TMAO affects cell type-specific pathways in mouse aorta, promoting atherosclerotic plaque instability by increasing apoptosis and reducing ECM formation.

13 citationstop 4%

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PhysiologybioRxivPreprintJul 18, 2025

Urinary Signatures Predict Calorie Restriction-Mediated Weight Loss in Obese Diversity Outbred Mice

Evan M. Paules, Isis Trujillo‐Gonzalez, Melissa VerHague…·Stephen David Hursting

The paper identifies urinary metabolite signatures predictive of calorie restriction-mediated weight loss in obese mice, with sex-specific differences observed.

1 citation

mousemetabolomics

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GeneticsbioRxivPreprintApr 25, 2023

Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation

Phillip Wulfridge, Adam Davidovich, Anna C. Salvador…·Andrew P. Feinberg

The paper uses mouse models to study diet-induced metabolic syndrome, identifies strain-specific transcriptional and epigenomic changes, and tests genotype-targeted pharmacological interventions.

DOI 10.1101/2023.04.25.538156

mousebulk RNA-seq

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