Author

Debodyuti Sadhukhan

National Institute of Immunology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Monica SunddiD· 2 shared Rashima PremiD· 2 shared Chetna Dhembla· 1 shared Garima Garima· 1 shared Shalini VermaiD· 1 shared Shivangi Vaish· 1 shared Suman Kundu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Monica SunddORCID

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2 papers

Recent·Most cited

A thioester-thiol exchange reaction in Salmonella Invasion acyl carrier protein transfers the 4PP-bound acyl chain to a distal cysteine

Rashima Prem, Garima Garima, Debodyuti Sadhukhan, Monica Sundd

This paper identifies a thioester-thiol exchange reaction in IacP that transfers the 4PP-bound acyl chain to a distal cysteine, revealing a mechanism for SipB acylation in Salmonella.

bioRxiv · Oct 26, 2026 · PreprintBiochemistry

A single mutation in the DSL motif of the acyl carrier protein can prevent its in vivo modification by E. coli Holo-acyl carrier protein synthase (AcpS)

Chetna Dhembla, Debodyuti Sadhukhan, Rashima Prem, Shivangi Vaish, Shalini Verma, Suman Kundu, Monica Sundd

The paper identifies a single mutation (D35N) in the DSL motif of acyl carrier proteins (ACP) that prevents in vivo modification by E. coli AcpS, enabling the expression of apo-ACP and demonstrating its applicability across different ACPs.

bioRxiv · Jan 28, 2025 · PreprintBiochemistry