HSP70 chaperones IL-33 in chronic airway disease
Omar A. Osorio, Colin E. Kluender, Heather E. Raphael, Ghandi F. Hassan, Lucy S. Cohen, Deborah F. Steinberg, Ella Katz-Kiriakos, Morgan D. Payne, Ethan M. Luo, Jamie L. Hicks, Derek E. Byers, Jennifer M Alexander‐Brett
This study identifies HSP70 as a chaperone that facilitates the secretion and activity of the IL-33{Delta}34 isoform in chronic airway diseases.
JCI Insight · Jun 24, 2025Peer-reviewedImmunology