Downregulation of Transducin Delays Photoreceptor Degeneration in P23H Rhodopsin Retinitis Pigmentosa
Deepa Mathew, Lee Sturgis, Marianna Mathison, Frans Vinberg
This study shows that reducing transducin in photoreceptors of P23H mice delays photoreceptor degeneration and improves function, suggesting transducin downregulation as a potential therapy for RP.
bioRxiv · Oct 4, 2025 · PreprintPhysiology