Bilateral JNK activation is a hallmark of interface contractility and promotes elimination of aberrant cells
Deepti Prasad, Katharina Illek, Friedericke Fischer, Katrin Holstein, Anne-Kathrin Classen
The paper identifies bilateral JNK activation as a hallmark of interface contractility that promotes elimination of aberrant cells in Drosophila imaginal discs, but oncogenic Ras evades this mechanism.
eLife · Feb 6, 2023Peer-reviewedDevelopmental Biology