Anne-Kathrin Classen

This study shows insecticide sensitivity in Drosophila varies with developmental stage, sex, temperature, and prior exposure, revealing context-dependent toxicity and potential trade-offs in stress resilience.

This study characterizes the dynamic changes in the inositol phosphate network during Drosophila melanogaster development using CE-MS and genetic perturbations, revealing stage-specific metabolic remodeling essential for metamorphosis and viability.

This study identifies long Toll receptors as mediators of interface surveillance in Drosophila wing imaginal discs, detecting cell fate aberrations through expression level differences between neighboring cells.

The paper shows that cell cycle dynamics regulate H3K27 and H3K9 histone modifications in Drosophila, with distinct mechanisms for acetylation and methylation.

This paper develops a deep learning pipeline to quantify epithelial cell shape and tight junctions, applied to ADPKD models and Drosophila egg chambers to study morphogenetic changes.

This study identifies E-Cadherin spot junctions as critical for soma-germline coupling during late Drosophila oogenesis, showing their role in mechanical coupling and nurse cell enveloping.

The paper identifies a metabolic pathway involving Pdk1/S6K and mTORC1 that allows regenerating tissues to bypass systemic growth restrictions induced by inflammation.

The paper identifies bilateral JNK activation as a hallmark of interface contractility that promotes elimination of aberrant cells in Drosophila imaginal discs, but oncogenic Ras evades this mechanism.

The paper shows that Eya controls cell-cell affinity between germline and somatic cells in Drosophila oogenesis, driving tissue self-organization through differential forces.

The paper identifies a mutual repression network between JNK/AP-1 and JAK/STAT signaling that spatially segregates cell behaviors during tissue regeneration in Drosophila.

The paper investigates how tension at epithelial adherens junctions integrates external forces to coordinate cell shape transitions and organ growth in Drosophila.