ROCK2 inhibition has a dual role in reducing ECM remodelling and cell growth, while impairing migration and invasion
Daniel A. Reed, Anna E. Howell, Nadia Kuepper, Alice M. H. Tran, Astrid Magenau, Deborah Sim Barkauskas, Max Nobis, Cecilia R. Chambers, Victoria Lee, Lily M. Channon, Jessie Zhu, Shona Ritchie, Janett Stoehr, Kaitlin Wyllie, Julia Chen, , David Herrmann
This paper shows that ROCK2 inhibition reduces ECM remodelling and cell growth while impairing migration and invasion in breast cancer models.
bioRxiv · Jul 21, 2025 · PreprintCell Biology