THE BILE ACID RECEPTOR TGR5 MODULATES HIPPOCAMPAL NEURAL STEM CELL STATE AND AGEING
Devanshu Kaushik, Prachi Dugam, Gourav Sarkar, Boda Arun Kumar, Sandip Kumar Patel, Sai Prasad Pydi, Prem N. Yadav
This study shows that TGR5 agonism expands hippocampal neural stem cells, reduces senescence, and improves cognitive function in aged mice without promoting neuronal differentiation.
bioRxiv · Oct 15, 2026 · PreprintNeuroscience