Prem Narayan Yadav

This study shows that TGR5 agonism expands hippocampal neural stem cells, reduces senescence, and improves cognitive function in aged mice without promoting neuronal differentiation.

This study investigates the role of H3R in DRG neurons and shows that an H3R inverse agonist reduces mechanical hypersensitivity in neuropathic pain without affecting thermal pain.

This paper identifies myeloid Gi signaling as a weight-independent immunometabolic switch that regulates systemic insulin sensitivity through opposing cytokine programs.

This study shows that CXCL10/CXCR3 signaling promotes neural senescence and cognitive impairments in mice, with effects blocked by a CXCR3 antagonist.

This study shows that KOR activation reduces BDNF expression in the PFC via HDAC5-mediated epigenetic silencing, contributing to depression-like symptoms in mice.