LSD persistently disrupts affective pain processing
Jared Plotkin, Elaine Zhu, Mélanie Druart, Qiaosheng Zhang, Eric Hu, Deven Cathcart, Nellie Jun, Leo Kwok, Tanya Sippy, Jing Wang
This study shows that a single dose of LSD in rats reduces pain affect by suppressing nociceptive responses in the anterior cingulate cortex.
bioRxiv · May 11, 2026 · PreprintNeuroscience