Firewalled synthetic commensal blocks horizontal gene transfer in the gut
Eric Hu, Kathryn Gorman Durben, Bogdan Budnik, Daniel H. Arlow, Sungwhan F. Oh, Ákos Nyerges
This paper develops a genetically firewalled Escherichia coli commensal that blocks horizontal gene transfer and viral infections while maintaining high fitness in the gut.
bioRxiv · Sep 18, 2026 · PreprintSynthetic Biology