LSD persistently disrupts affective pain processing
Jared Plotkin, Elaine Zhu, Mélanie Druart…·Jing Wang
This study shows that a single dose of LSD in rats reduces pain affect by suppressing nociceptive responses in the anterior cingulate cortex.
Author
Capital Medical UniversityORCID 0000-0003-1580-1356Unclaimed ORCID profile · follow to get notified of new preprints
9 papers
Recent·Most cited
Jared Plotkin, Elaine Zhu, Mélanie Druart…·Jing Wang
This study shows that a single dose of LSD in rats reduces pain affect by suppressing nociceptive responses in the anterior cingulate cortex.
Eric Hu, Guanghao Sun, Elaine Zhu…·Jing Wang
This study identifies a hierarchical cortical circuit involving the prelimbic and anterior cingulate cortex that modulates pain behavior through synaptic, cellular, and network-level mechanisms.
Sifan Meng, Xiaowei Sha, Guoyan Zhang…·Wei Ding
This study identifies ZNF638 as a host factor that represses HBV transcription by recruiting the HUSH complex to induce H3K9me3 histone modifications, thereby silencing cccDNA and reducing viral propagation.
Qian Wang, Lu Luo, Na Xu…·Fang Fang
This study identifies neural response features that predict perceived sound content and location from intracranial electrical stimulation in human auditory cortex.
Ernie Yulyaningsih, Jung H. Suh, Melania H. Fanok…·Pascal E. Sanchez
DNL343 reduces neurodegeneration in mouse models by inhibiting the integrated stress response and normalizing dysregulated biomarkers, with potential clinical relevance for vanishing white matter disease.
Ying Yu, Wanwan Hou, Haiyan Wang…·Yuanting Zheng
The paper introduces RNA reference materials and ratio-based datasets to improve the reliability and benchmarking of transcriptomic profiling.
Tingting Li, Tian Xia, Jiaqi Wu…·Tao Li
This paper presents a high-quality cattle genome assembly with improved continuity and completeness, revealing the highest known immune gene diversity in mammals.
Yuru Song, Mingchen Yao, Helen Kemprecos…·Zhe Sage Chen
This paper develops predictive coding models to study pain perception by analyzing neural activity in rats, revealing insights into how expectation and chronic pain influence neural dynamics.
Qian Wang, Lu Luo, Na Xu…·Guoming Luan
This study investigates the role of insular and supra-temporal auditory areas in humans using intracranial recordings and stimulation, finding that while insula has similar auditory responses, it does not directly contribute to auditory perception.