Defects in nephrogenesis result in an expansion of the Foxd1+ stromal progenitor population
Michael G. Michalopulos, Yan Liu, Dinesh Ravindra Raju, John T. Lafin, Yanru Ma, Dhruv Gaur, Sadiksha Khadka, Chao Xing, Andrew P. McMahon, Thomas J. Carroll, Keri A. Drake
The paper shows that defects in nephron progenitor cell differentiation lead to an expansion of Foxd1+ stromal progenitors in mouse models and identifies a conserved subcluster in human fetal kidneys.
Development · Dec 8, 2025Peer-reviewedDevelopmental Biology