Molecular BiologyMolecular Genetics and MetabolismPeer-reviewed
AAV-mediated expression of mouse or human GLDC normalises metabolic biomarkers in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia
Kit‐Yi Leung, Chloe Santos, Sandra C. de Castro…·Nicholas D. E. Greene
This study demonstrates that AAV-mediated GLDC expression reduces glycine levels and normalizes folate metabolism in a GLDC-deficient mouse model of NKH.
6 citations