Author

Chloe Santos

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Andrew J. CoppiD· 2 shared Nicholas D. E. GreeneiD· 2 shared Sandra C. de CastroiD· 2 shared Abigail R. MarshalliD· 1 shared Ailish Murray· 1 shared Anna C. ThomasiD· 1 shared Diana Gold Diaz· 1 shared Dianne GerrelliiD· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Andrew J. CoppORCID

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3 papers

Recent·Most cited

Spinal neural tube formation and tail development in human embryos

Chloe Santos, Abigail R. Marshall, Ailish Murray, Kate Metcalfe, Priyanka Narayan, Sandra C. de Castro, Eirini Maniou, Nicholas D. E. Greene, Gabriel L. Galea, Andrew J. Copp

This study examines spinal neural tube formation and tail development in human embryos, finding patterns similar to mouse and rat, including primary neurulation completion and secondary neurulation characteristics.

eLife · Dec 5, 2024Peer-reviewedDevelopmental Biology

AAV-mediated expression of mouse or human GLDC normalises metabolic biomarkers in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia

Kit‐Yi Leung, Chloe Santos, Sandra C. de Castro, Diana Gold Diaz, Andrew J. Copp, Simon N. Waddington, Nicholas D. E. Greene

This study demonstrates that AAV-mediated GLDC expression reduces glycine levels and normalizes folate metabolism in a GLDC-deficient mouse model of NKH.

Molecular Genetics and Metabolism · May 15, 2024Peer-reviewedMolecular Biology

Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic development

Anna C. Thomas, Pauline Heux, Chloe Santos, Wisenave Arulvasan, Nita Solanky, Magalie E. Carey, Dianne Gerrelli, Veronica A. Kinsler, Heather Etchevers

The paper shows MC1R is widely expressed in non-cutaneous tissues during embryonic development across chick, mouse, and human, with potential pleiotropic effects on birthweight.

Birth Defects Research · Jan 8, 2018Peer-reviewedDevelopmental Biology