Co-release of histamine and GABA in prefrontal cortex excites fast-spiking interneurons and causes divisive gain change in pyramidal cells; an effect that is enhanced in older mice
Diana Lucaci, Xiao Hong Yu, Paul T. Chadderton, William Wisden, Stephen G. Brickley
The paper investigates how histamine and GABA co-release from TMN axons affects PFC neuron excitability, showing increased inhibition in pyramidal cells and enhanced effects in older mice.
bioRxiv · Mar 11, 2022 · PreprintNeuroscience