Paul T. Chadderton

Stable fusion of bone marrow-derived cells with Purkinje neurons enables long-term nuclear integration and neuronal repair

The paper demonstrates that bone marrow-derived cells can stably fuse with Purkinje neurons in vivo, maintaining functional integration over time.

Tactile stimulation transiently disrupts encoding of whisker position by cerebellar molecular layer interneuron ensembles

The paper shows that tactile stimulation disrupts the encoding of whisker position by cerebellar MLIs, suggesting a role in sensory feedback integration.

Cerebellar-driven cortical dynamics enable task acquisition, switching and consolidation

This study introduces a computational model showing cerebellar feedback enables rapid task acquisition, switching, and consolidation through cortical dynamics.

GlyT2-positive interneurons regulate timing and variability of information transfer in a cerebellar-behavioural loop

This study investigates the role of GlyT2-positive interneurons in cerebellar network dynamics and behaviour, finding they modulate the timing of population activity rather than sensorimotor representations.

Cerebellar state estimation enables resilient coupling across behavioural domains

This paper proposes a cerebellar model for state estimation that links neuronal dynamics with behavioral coordination, using the free energy principle to explain contextual behavior.

Cerebro-cerebellar networks facilitate learning through feedback decoupling

This paper introduces a computational model of cerebro-cerebellar interactions that decouples learning from feedback, showing improved performance in motor and cognitive tasks.

Co-release of histamine and GABA in prefrontal cortex excites fast-spiking interneurons and causes divisive gain change in pyramidal cells; an effect that is enhanced in older mice

The paper investigates how histamine and GABA co-release from TMN axons affects PFC neuron excitability, showing increased inhibition in pyramidal cells and enhanced effects in older mice.