Determinants of membrane sensitivity to the peptide MP-1 (Polybia paulista)
Andrew Booth, Arindam Pramanik, Dagmara Kobza, Didi Derks, Lekshmi Kailas, William J. Brackenbury, Simon D. Connell, Thomas A. Hughes, Paul A. Beales
The paper identifies MP-1 peptide mutants with enhanced selectivity for cancer-like membranes and breast cancer cells, revealing structure-activity relationships through model membranes and cell assays.
bioRxiv · Sep 17, 2025 · PreprintBiophysics