The Ubiquitin-Proteasome Pathway Mediates Selective Degradation of Unloaded Argonautes in C. elegans
Jenny M Zhao, Dieu An H. Nguyen, Diego Cervantes, Brandon Vong, Carolyn M. Phillips
The paper shows that unloaded Argonaute proteins in C. elegans are degraded by the ubiquitin-proteasome system, highlighting a quality control mechanism for small RNA-loaded Argonautes.
Genetics · Jan 13, 2026Peer-reviewedGenetics