Urothelial organoids originate from Cd49f-High stem cells and display Notch-dependent differentiation capacity
Catarina P. Santos, Eleonora Lapi, Laura Álvaro-Espinosa, Asunción Fernández-Barral, Antonio Barbáchano, Diego Megías, Alberto Muñoz, Francisco X Real
This study establishes a method to propagate urothelial organoids from Cd49f-high stem cells and identifies Notch signaling as critical for their differentiation.
bioRxiv · Mar 23, 2018 · PreprintCell Biology