Author

Diep H. Nguyen

Whitehead Institute for Biomedical Research

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Immunology· 1

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Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Connie WangiD· 1 shared Jiakun TianiD· 1 shared Pulin LiiD· 1 shared Sean-Luc ShanahaniD· 1 shared Tyler JacksiD· 1 shared Xiao WangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Connie WangORCID

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1 paper

Recent·Most cited

A tissue-scale strategy for sensing threats in barrier organs

Diep H. Nguyen, Jiakun Tian, Sean-Luc Shanahan, Connie Wang, Tyler Jacks, Xiao Wang, Pulin Li

The paper uses single-molecule imaging and spatial transcriptomics to show a spatially graded threat-sensing strategy in lung tissue during influenza infection, with higher PRR expression in inner stroma leading to more potent immune responses.

Cell Systems · May 15, 2026Peer-reviewedImmunology