ImmunologyCell SystemsPeer-reviewed
A tissue-scale strategy for sensing threats in barrier organs
Diep H. Nguyen, Jiakun Tian, Sean-Luc Shanahan…·Pulin Li
The paper uses single-molecule imaging and spatial transcriptomics to show a spatially graded threat-sensing strategy in lung tissue during influenza infection, with higher PRR expression in inner stroma leading to more potent immune responses.