Human hematopoietic stem cell vulnerability to ferroptosis
Jiawei Zhao, Yuemeng Jia, Dilnar Mahmut, Amy Deik, Sarah Jeanfavre, Clary B. Clish, Vijay G. Sankaran
This study identifies ferroptosis as a vulnerability in human hematopoietic stem cells (HSCs) linked to reduced protein synthesis, showing that blocking ferroptosis rescues HSC maintenance.
Cell · Feb 1, 2023Peer-reviewedGenetics