Author

Sarah Jeanfavre

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2 Genetics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:metabolomics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Clary B. ClishiD· 4 shared Amy DeikiD· 3 shared Courtney DennisiD· 3 shared Daniel S. HitchcockiD· 2 shared Jesse KrejciiD· 2 shared Julián Ávila-PachecoiD· 2 shared Kerry A. PierceiD· 2 shared Kevin H. BullockiD· 2 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBioinformatics

Clary B. ClishORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Eclipse: A Python package for alignment of two or more nontargeted LC-MS metabolomics datasets

Daniel S. Hitchcock, Jesse Krejci, Chloe E Sturgeon, Courtney Dennis, Sarah Jeanfavre, Julián Ávila-Pacheco, Clary B. Clish

Eclipse aligns multiple nontargeted LC-MS metabolomics datasets using a graph-based subalignment approach.

Bioinformatics · May 10, 2025Peer-reviewedBioinformatics

Human hematopoietic stem cell vulnerability to ferroptosis

Jiawei Zhao, Yuemeng Jia, Dilnar Mahmut, Amy Deik, Sarah Jeanfavre, Clary B. Clish, Vijay G. Sankaran

This study identifies ferroptosis as a vulnerability in human hematopoietic stem cells (HSCs) linked to reduced protein synthesis, showing that blocking ferroptosis rescues HSC maintenance.

Cell · Feb 1, 2023Peer-reviewedGenetics

Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis

Alina Ainbinder, Liping Zhao, Patricia Glover, Karen Gelinas-Roa, Victor Rusu, Alycen M. Harney, Eitan Hoch, Amy Deik, Kerry A. Pierce, Kevin H. Bullock, Courtney Dennis, Sarah Jeanfavre, Jesse Krejci, Jinyoung Choi, Anthony Neil Hollenberg, , Suzanne B.R. Jacobs

This study shows that Mct11 deficiency in mice disrupts hepatic glucose and lipid metabolism, mirroring T2D features, and identifies MCT11 as a potential therapeutic target for T2D.

bioRxiv · Sep 8, 2021 · PreprintGenetics

netome: a computational framework for metabolite profiling and omics network analysis

Ali Rahnavard, Daniel S. Hitchcock, Julián Ávila-Pacheco, Amy Deik, Courtney Dennis, Sarah Jeanfavre, Kerry A. Pierce, Kevin H. Bullock, Zachary A. Costliow, Clary B. Clish

netome provides tools for analyzing LC-MS metabolomics data, including quality control, peak alignment, and network-based statistical testing.

bioRxiv · Oct 16, 2018 · PreprintBioinformatics