Synthetic BiologyScientific ReportsPeer-reviewed
Computational redesign of the Escherichia coli ribose-binding protein ligand binding pocket for 1,3-cyclohexanediol and cyclohexanol
Diogo Tavares, Artur Reimer, Shantanu Roy…·Jan Roelof van der Meer
The paper computationally redesigns the Escherichia coli RbsB ribose-binding protein to recognize non-natural ligands 1,3-cyclohexanediol and cyclohexanol, achieving partial success with some mutants showing ligand-specific induction.
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