Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction
Yoshiko Matsumoto Ikushima, Kuan-Chan Chen, Richard J. Sulston, Domenico Mattiucci, Eleanor J Brain, Stefanie A Fung Xin Zi, Karla J. Suchacki, Benjamin J. Thomas, Andrea Lovdel, Matthew Bennett, Hiroshi Kobayashi, Phillip D. Whitfield, Keiyo Takubo, Andrew Howard Baker, Nicholas M. Morton, , William Peter Cawthorn
This study shows adiponectin influences sex-specific metabolic changes during caloric restriction, affecting glucose, lipid, and amino acid metabolism through hepatic mechanisms.
PLoS Biology · Jun 18, 2026Peer-reviewedPhysiology