Author

Dona Bruening

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

Berit E. PowersiD· 1 shared Curt MazuriD· 1 shared Eric E. SwayzeiD· 1 shared Hans J. GausiD· 1 shared Hao CheniD· 1 shared Hien Tran ZhaoiD· 1 shared Holly B. KordasiewicziD· 1 shared Jacqueline G. O’Rourke· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Berit E. PowersORCID

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Author profile →

1 paper

Recent·Most cited

Transient Acute Neuronal Activation Response Caused by High Concentrations of Oligonucleotides in the Cerebral Spinal Fluid

Mariana Bravo Hernandez, Curt Mazur, Hao Chen, Linda Fradkin, Justin Searcy, Sebastien A. Burel, M Elizabeth Kelly, Dona Bruening, Jacqueline G. O’Rourke, Yuhang Cai, Jonathon Nguyen, Lisa D. Berman-Booty, Lendell L. Cummins, Hans J. Gaus, Berit E. Powers, , Holly B. Kordasiewicz

The paper characterizes a transient neurobehavioral response to high-dose oligonucleotide delivery in the CNS and provides a framework to mitigate it through magnesium supplementation.

bioRxiv · Feb 13, 2025 · PreprintNeuroscience