Dynamic responses of human lung innate and adaptive immune cells highlight the roles of genes at asthma risk loci
Funing Tian, Donna C Decker, Anne I. Sperling, Nathan Schoettler
The paper examines gene expression in human lung immune cells after stimulation, finding that genes at asthma risk loci show differential expression and that B cells express HLA-DQA2 and HLA-DQB2, suggesting a novel antigen presentation pathway in asthma.
bioRxiv · Sep 20, 2024 · PreprintImmunology