A new class of inherently efficient SUMOylation substrates
El hadji Cisse, Laura Visticot, Rafael Cepa, Aanchal Mishra, Franck Coste, Stéphane Goffinont, Lucija Mance, Sarah Battault, Dorian Guigneau, Ibtissam Talhaoui, Bertrand Castaing, Vincent Aucagne, Pierre‐Antoine Defossez, Marcin J. Suskiewicz
This paper identifies a new class of inherently efficient SUMOylation substrates by showing that ZBTB38BTB and related BTB domains can be SUMOylated efficiently without E3 ligase involvement.
bioRxiv · Sep 13, 2026 · PreprintBiochemistry