Whole genome sequencing in multiplex families reveals novel inherited and de novo genetic risk in autism
Elizabeth K. Ruzzo, Laura Pérez‐Cano, Jae-Yoon Jung, Lee-kai Wang, Dorna Kashef-Haghighi, Christopher Hartl, Jackson N. Hoekstra, Olivia Leventhal, Michael J. Gandal, Kelley Marie Paskov, Nate Stockham, Damon Polioudakis, Jennifer K. Lowe, Daniel H. Geschwind, Dennis Paul Wall
This study uses whole-genome sequencing in multiplex families to identify novel inherited and de novo genetic risk factors for autism, revealing 16 new ASD-risk genes and supporting 69 total genes.
bioRxiv · Jun 6, 2018 · PreprintGenomics