Author

Damon Polioudakis

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Daniel H. GeschwindiD· 5 shared Andrew G. Elkins· 2 shared Elizabeth K. RuzzoiD· 2 shared Jennifer K. LoweiD· 2 shared Luis de la Torre-UbietaiD· 2 shared Riki KawaguchiiD· 2 shared Adam M. H. Young· 1 shared Ajay NadigiD· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersNeuroscience

Daniel H. GeschwindORCID

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Author profile →

5 papers

Recent·Most cited

Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics

Jessica E. Rexach, Yuyan Cheng, Lawrence Chen, Damon Polioudakis, Li‐Chun Lin, Vivianne Mitri, Andrew G. Elkins, Anna Yin, Daniela Calini, Riki Kawaguchi, Jing Ou, Jerry I. Huang, Christopher Williams, John L. Robinson, Stephanie E. Gaus, , Daniel H. Geschwind

The paper uses single-cell genomics to identify shared and disease-specific cell states and gene regulatory networks in three dementias, revealing distinct neuroimmune mechanisms and potential therapeutic targets.

bioRxiv · Sep 29, 2023 · PreprintNeuroscience

Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders

Jakob Seidlitz, Ajay Nadig, Siyuan Liu, Richard A. I. Bethlehem, Petra E. Vértes, Sarah Elizabeth Morgan, František Váša, Rafael Romero-García, François M. Lalonde, LIV S. CLASEN, Jonathan D. Blumenthal, Casey Paquola, Boris C. Bernhardt, Konrad Wagstyl, Damon Polioudakis, , Armin Raznahan

The paper links genetic risks to spatial brain vulnerabilities in neurodevelopmental disorders using neuroimaging and gene expression data.

bioRxiv · Nov 17, 2019 · PreprintNeuroscience

Single-cell in situ transcriptomic map of astrocyte cortical layer diversity

Omer Ali Bayraktar, Theresa Bartels, Damon Polioudakis, Staffan Holmqvist, Lucile Ben Haim, Adam M. H. Young, Kirti Prakash, Alexander P.Y. Brown, Mercedes F. Paredes, Riki Kawaguchi, John H. Stockley, Khalida Sabeur, Sandra Chang, Eric Jinsheng Huang, Peter J. Hutchinson, , David H. Rowitch

The paper maps astrocyte layer diversity in the cortex using a high-content spatial transcriptomic pipeline, revealing distinct astrocyte identities and their relationship to neuronal organization.

bioRxiv · Oct 3, 2018 · PreprintNeuroscience

A single cell transcriptomic analysis of human neocortical development

Damon Polioudakis, Luis de la Torre-Ubieta, Justin Langerman, Andrew G. Elkins, Jason L. Stein, Celine K. Vuong, Carli K. Opland, Daning Lu, William Connell, Elizabeth K. Ruzzo, Jennifer K. Lowe, Tarik Hadžić, Flora I. Hinz, Shan Sabri, William E. Lowry, , Daniel H. Geschwind

The paper defines single cell transcriptomic profiles of 40,000 human neocortical cells to identify cell types, developmental trajectories, and disease-related gene expression.

bioRxiv · Aug 28, 2018 · PreprintNeuroscience

Whole genome sequencing in multiplex families reveals novel inherited and de novo genetic risk in autism

Elizabeth K. Ruzzo, Laura Pérez‐Cano, Jae-Yoon Jung, Lee-kai Wang, Dorna Kashef-Haghighi, Christopher Hartl, Jackson N. Hoekstra, Olivia Leventhal, Michael J. Gandal, Kelley Marie Paskov, Nate Stockham, Damon Polioudakis, Jennifer K. Lowe, Daniel H. Geschwind, Dennis Paul Wall

This study uses whole-genome sequencing in multiplex families to identify novel inherited and de novo genetic risk factors for autism, revealing 16 new ASD-risk genes and supporting 69 total genes.

bioRxiv · Jun 6, 2018 · PreprintGenomics