Author

Douglas C Wallace

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Chunjie LiuiD· 1 shared Gabrielle Widjaja· 1 shared Liming PeiiD· 1 shared Marie T. LottiD· 1 shared Peiran LuiD· 1 shared Po HuiD· 1 shared Prasanth PotluriiD· 1 shared Shiping ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Chunjie LiuORCID

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1 paper

Recent·Most cited

Single-cell variant landscape of the human mitochondrial genome reveals cell type-specific functions and disease mechanisms

Chunjie Liu, Ting Peng, Zimu Cen, Peiran Lu, Prasanth Potluri, Po Hu, Shiping Zhang, Marie T. Lott, Gabrielle Widjaja, Douglas C Wallace, Yi Xing, Liming Pei

The paper presents scMOCHA, a tool to analyze mtDNA heteroplasmy from scRNA-seq data, revealing cell type-specific mtDNA variants and disease mechanisms in hematopoietic cells.

bioRxiv · Oct 13, 2026 · PreprintGenetics